pH - sensitive fusogenic 3 - methyl - glutarylated hyperbranched 1 poly ( glycidol ) ( MGlu - HPG ) - conjugated liposome induces 2 antigen - specific cellular and humoral immunity
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چکیده
pH-sensitive fusogenic 3-methyl-glutarylated hyperbranched 1 poly(glycidol) (MGlu-HPG)-conjugated liposome induces 2 antigen-specific cellular and humoral immunity 3 4 Takehisa Hebishima, 4 Eiji Yuba, Kenji Kono, Shin-nosuke Takeshima, Yoshihiro 5 Ito, and Yoko Aida 6 7 1 Viral Infectious Diseases Unit, and Nano Medical Engineering Laboratory, RIKEN, 8 2-1 Hirosawa, Wako, Saitama 351-0198, Japan 9 Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture 10 University, 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8531, Japan 11 Invited Research Fellow, Graduate School of Agricultural and Life Sciences, University 12 of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan 13 *Correspondence author. Mailing address: Viral Infectious Diseases Unit, RIKEN, 2-1 14 Hirosawa, Wako, Saitama 351-0198, Japan; Tel.: +81-48-462-4408; Fax.: 15 +81-48-462-4399; E-mail: [email protected] 16 17 Running title: Adjuvant activity of polymer-modified liposome 18 19 Copyright © 2012, American Society for Microbiology. All Rights Reserved. Clin. Vaccine Immunol. doi:10.1128/CVI.00273-12 CVI Accepts, published online ahead of print on 18 July 2012
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تاریخ انتشار 2012